Teens who have used psychedelics may have lower rates of psychotic symptoms

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A study of twins has found that the use of psychedelics may be linked to lower rates of psychotic symptoms at age 15, although for teens with a higher genetic vulnerability to schizophrenia or bipolar I disorder, it was linked to more manic symptoms. The researchers say this indicates that mania following psychedelic use may be more likely in individuals with a personal or family history of schizophrenia or bipolar I disorder.

Journal/conference: JAMA Psychiatry

Link to research (DOI): 10.1001/jamapsychiatry.2024.0047

Organisation/s: The University of Melbourne, Karolinska Institutet, Sweden

Funder: This study was supported by the
Ekhaga Foundation (2021-59) and Olle Engkvist
Foundation (218-0049). Dr Lu is supported by the
US National Institutes of Mental Health (R01
MH123724), the European Union’s Horizon 2020 Research and Innovation Program (964874),
and the European Research Council (101042183).


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